GPAT (Graduate Pharmacy Aptitude Test) 2018 Exam Pattern

Last Updated - February 23 2018

GPAT (Graduate Pharmacy Aptitude Test) 2018 Exam Pattern

GPAT 2018, designated as Graduate Pharmacy Aptitude Test 2018 is an online National Level Entrance Test being organizeed by All India Council of Technical Education, AICTE. Via this test, aspirants can get admission in the postgraduate course in Pharmacy, the M.Pharma course.

  • GPAT 2018 consists of 125 questions and aspirant is given 180 minutes to clear the test.
  • There is negative marking in GPAT 2018.
  • The overall difficulty level in GPAT is easy to moderate level of difficulty. Check GPAT Earlier Year Papers
  • GPAT 2018 is an online exam which is organizeed once a year.
  • Syllabus of GPAT 2018 comprises topics from the undergraduate curriculum prescribed by PCI (Pharmacy Council of India).

Exam Format Highlights of GPAT 2018

Name of examGraduate Pharmacy Aptitude Test 2018
Commonly known asGPAT 2018
FrequencyOnce a year
Number of questions125
Time gave180 minutes
Negative MarkingYes

Exam Format Details of GPAT 2018

As stated previous, GPAT 2018 is going to be an online test in which aspirants will be allotted computers to perform the test. GPAT 2018 will be held once in a year and tentatively it is expected to be organizeed in last week of January 2018.

Here are some details about the exam format of GPAT 2018:-

  • Questions in GPAT 2018 will be Multiple Choice Type (MCQ) questions. Aspirant will have to mark his/her response from 4 options available.
  • Aspirants can visit the official website (, where they can take the online trial test for GPAT 2018 so that they can have more knowledge of Exam Format of GPAT 2018.
  • Aspirants will be allotted a total time of 180 minutes to clear the whole test.
  • GPAT 2018 will include 125 which will relate to various subjects like Chemistry and Pharmaceutics.

Also, Read Top GPAT Coaching Centers in India

Marking Scheme of GPAT 2018

Marking scheme of GPAT 2018 is fairly simple. GPAT 2018 does have the provision of negative marking thus aspirants required to be careful about their choice.

Let’s take a look at some of the details about marking scheme of GPAT 2018:

  • Leaving a question or not attempting a question does not attract any negative marking in GPAT 2018.
  • For every inaccurate answer in GPAT, 1 mark will be deducted. Thus, provision of negative marking up to 1/4th of the value of the question is eligible.
  • Each question carries a weightage of 4 marks, thus, the total maximum possible score in GPAT 2018 is 500.

The following table may sum up the marking scheme in GPAT  in brief:

If aspirant marks the right response+4 marks in the total
If aspirant marks the wrong response-1 marks from the total
If aspirant does not mark any choice or simply does not attempt any question0 marks honored

Syllabus of GPAT 2018

GPAT 2018 Syllabus is to be decided by AICTE and can be changed by the authority from year to year. GPAT 2018 Syllabus will cover vast aspects concerned with pharmaceuticals, such as Chemistry, Engineering, Management, Technology and even legal and regulatory knowledge about pharmaceutical business.

GPAT 2018 demands a big horizon of knowledge from aspirant. Here is a clear list of topics and subjects to be covered in the exam:

Physical ChemistryComposition and physical states of matter, Colligative properties, Thermodynamics, Chemical equilibria, Phase rule, Refractive index, Solutions, Electrochemistry, Ionic equilibrium, Kinetics
Physical PharmacyMatter, properties of matter, Micromeritics and powder rheology, Surface and interfacial phenomenon, Viscosity and rheology, Dispersion systems, Complexation, Buffer, Solubility
Organic ChemistryGeneral principles, Various classes of compounds, Protection and deprotection of groups, Aromaticity and aromatic chemistry, Various aromatic classes of compounds, Polycyclic aromatic hydrocarbons, Carbonyl chemistry, Heterocyclic chemistry, Bridged rings, Kinetic and thermodynamic control, Stereochemistry, Carbohydrates, Amino acids and proteins, Organometallic chemistry, Pericyclic reactions
Pharmaceutical ChemistryPharmaceutical impurities, Monographs, Isotopes, Therapeutic classes of drugs, Drug metabolism, Different classes of therapeutic agents, Various classes of therapeutic drugs
PharmaceuticsPharmacy profession, Introduction to pharmaceuticals, Introduction to dosage form, Route of administration, ADME, Sources of drug information, Allopathic dosage form, Crude extract, Allergenic extract Ayurvedic system of medicine, Homeopathic system of medicine, Biological products, GMP, Pharmaceutical plant, location, layout Dosage form necessities and additives, Powders, Capsules, Tablets Parenterals – products requiring sterile packaging, Suspensions Emulsions, Suppositories, Semisolids, Liquids, Pharmaceutical aerosols Ophthalmic preparations, Preformulations , Radio pharmaceuticals Stability of formulated products, Kinetic principles and stability testing Prolonged action pharmaceuticals, Novel drug delivery system, Cosmetics, Packaging material, GMP and validation, Pilot plant scale up techniques
PharmacologyGeneral pharmacology, Pharmacology for peripheral nervous system, Pharmacology of cardiovascular system, Drugs acting on urinary system, Drugs acting on respiratory system, Pharmacology of central nervous system, Pharmacology of endocrine system, Chemotherapy, Autacoids and their antagonists, Pharmacology of drugs acting on gastrointestinal tract, Chronopharmacology, Immunopharmacology, Chemotherapy of malignant diseases, Peptides and proteins as mediators, Nitric oxide, Vitamins and minerals, Principles of toxicology
PharmacognosyIntroductory Pharmacognosy, Classification of crude drugs, Sources of crude drugs, Factors influencing quality of crude drugs, Techniques in microscopy, Introduction to phytoconstituents, Principles of plant classification, Pharmaceutical aids, Animal products, Plant products, Toxic drugs, Enzymes, Natural pesticides and insecticides, Adulteration and evaluation of crude drugs, Quantitative microscopy, Biogenetic pathways, Carbohydrates and lipids, Tannins, Volatile oils, Resinous drugs, Glycocides, Alkaloids, Herbarium, Extraction and isolation techniques, Phytopharmaceuticals, Quality control and standardization of herbal drugs, Herbal formulations, Worldwide trade of crude drugs and volatile drug, Plant biotechnology, Herbal cosmetics, Traditional herbal drugs, Plant based industries and research institutes in India Patents
Pharmaceutical AnalysisImportance of quality control in pharmacy, Acid-base titrations, Non-aqueous titrations, Oxidation-reduction titrations, Precipitation titrations, Complexometric titrations, Gravimetry, Extraction techniques , Potentiometry, Miscellaneous methods of analysis, Calibration General principles of spectroscopy, Ultraviolet-visible spectrometry Spectrofluorimetric, Flame photometry and atomic absorption spectrometry, Infrared spectrometry, Proton nuclear magnetic resonance spectrometry, Mass spectrometry, Polarography, Nephelometry and turbidimetry, Chromatography
BiochemistryCell, Carbohydrates, Proteins, Lipids, Vitamins, Biological oxidations and reductions, Enzymes, Nucleic Acids, Hereditary diseases
BiotechnologyPlant cell and tissue culture, Animal cell structure, Fermentation technology and industrial microbiology, Recombinant DNA Technology, Procedure and applications, Biotechnology-derived products, Proteomics, Formulation of proteins and peptides
MicrobiologyIntroduction to microbiology, Microscopy and staining technique, Biology of microorganisms, Fungi and viruses, Asceptic technique, Sterilization and disinfection, Microbial spoilage, Immunology and health, Vaccines and sera, Microbial assay
PathophysiologyBasic principles of cell injury and adaptation, Basic mechanism of inflammation and repair, Hypersensitivity, Autoimmunity and diseases of immunity, Neoplastic diseases, Shock, Biological effects of radiation, Protein-calorie malnutrition, vitamins, Obesity and starvation, Pathophysiology of common diseases, Infectious diseases
Biopharmaceutics and PharmacokineticsBio-pharmaceutics, Bio-availability and bio-equivalence, Bio-pharmaceutical statistics
Pharmaceutical ManagementIntroduction to management, Planning and forecasting, Organization, Research management, Inventory management, Communication, Marketing research, Leadership and motivation, Human resource development, GATT, WTO and TRIPS, Standard institutions and regulatory authorities
Pharmaceutical EngineeringFluid flow, Heat transfer, Evaporation, Distillation, Drying, Size reduction and size separation, Extraction, Mixing, Crystallization, Filtration and centrifugation, Dehumidification and humidity control, Refrigeration and air conditioning, Material of constructions, Automated procedure control systems, Industrial hazards and safety precautions
Dispensing and Hospital PharmacyIntroduction to laboratory equipment, weighting methodology, handling of prescriptions, labelling instructions for dispensed products. Preparations based on percolation procedure. Preparations based on maceration procedure. Study of difference between marketed and dispensed products of various dosage forms. Posological calculations involved in the calculation of dosage for infants. Enlarging and reducing formula, displacement value. Preparations of formulations involving allegation, alcohol dilution, isotonic solution.
Pharmaceutical JurisprudenceHistorical background Drug legislation in India, Code of Ethics for Pharmacists, The Pharmacy Act 1948 (inclusive of recent amendments), Drugs and Cosmetics Act 1940, Rules 1945, including New Drug applications, Narcotic Drugs and Psychotropic Substances Act, and Rules there under, Drugs and Magic Remedies (Objectionable Advertisements) Act 1954, Medicinal and Toilet Preparations (Excise Duties) Act 1955, Rules 1976, Medical Termination of Pregnancy Act 1970 and Rules 1975, Prevention of Cruelty to Animals Act 1960, Drug (Price Control) Order, Shops and Foundment Act, Factory Act, Consumer Protection Act, Indian Pharmaceutical Industry- An Overview, Industrial Development and Regulation act 1951, Introduction to Intellectual Property Rights and Indian Patent Act 1970,An Introduction to Standard Institutions and Regulatory Authorities such as BIS, ASTM, ISO, TGA, USFDA, MHRA, ICH, WHO, At Least Wages Act 1948, Prevention of Food Adulteration Act 1954 and Rules 1955.
Clinical pharmacy and therapeuticsGeneral Principles, preparation, maintenance, analysis of observational records in Clinical Pharmacy, Clinical trials, type and phases of clinical trials, placebo, ethical and regulatory issues including Good clinical exercise in clinical trials, Therapeutic drug monitoring, adverse drug reaction (ADR), types of ADR, Mechanism of ADR. Drug interaction, Monitoring and reporting of ADR and its significance, Drug information services, Drug interactions, Drug interaction in pediatric and geriatric patients, drug treatment during pregnancy, lactation and menstruation, Pharmacovigilance, Therapeutic drug monitoring, Nutraceuticals, essential drugs and rational drug usage, Age concerned drug therapy: concept of posology, drug therapy for neonates, pediatrics and geriatrics. Drugs used in pregnancy and lactation, Drug therapy in gastrointestinal, hepatic, renal, cardiovascular and respiratory Disorders, Drug therapy for neurological and psychological disorders, Drug therapy in infections of the respiratory system, urinary system, infective meningitis, TB, HIV, malaria and filaria. Drug therapy for thyroid and parathyroid disorders, diabetes mellitus, menstrual cycle disorders, menopause and male sexual dysfunction, Drug therapy for malignant disorders like leukaemia, lymphoma and solid tumours, Drug therapy for rheumatic, eye and skin disorders.

Download GPAT Syllabus PDF

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